Fluid Management & Irrigation Control in UBE
Hydrodynamic principles · Pressure settings · Prevention of irrigation-related complications
#Why Fluid Management Matters
Unilateral biportal endoscopic (UBE) spine surgery differs from microscopic surgery in one essential way: it is performed in a continuous saline irrigation environment. Under the microscope, the surgical field is visualized in air; in UBE, saline is the medium itself, and the flow and pressure of that saline are part of the operation.
A recent multicenter observational study reported that UBE consumes a median of 9 liters of saline per case, roughly 112 times the volume used in conventional microdiscectomy (median 0.08 L). This is not merely a difference in volume — it reflects the fact that fluid serves three simultaneous functions: maintaining visualization, supporting hemostasis, and clearing tissue debris.
At the same time, fluid is the single greatest source of risk in UBE. Inadequate pressure control can produce an epidural pressure spike, leading to seizure, postoperative headache, or neurologic deficit; obstructed outflow can result in fluid extravasation, retroperitoneal effusion, or neck swelling. Seizure after percutaneous endoscopic spine surgery has been reported at 0.52%, with a mean intraoperative irrigation rate of 109 mL/min.
Working portal triangulation establishes the geometric foundation of the working zone; fluid management establishes its hydrodynamic foundation. This article addresses the inflow–outflow principle, optimal pressure settings, and practical steps for preventing irrigation-related complications in UBE.
#The Hydrodynamic Principle: Inflow vs Outflow
The UBE fluid system operates as an equilibrium between inflow and outflow through two portals. Inflow enters through the endoscope sheath; outflow exits naturally through the working portal. When the two streams are balanced, working-space pressure remains stable and dural pulsation is preserved.
The central concept is this: the working portal is not merely a conduit for instruments — it simultaneously functions as the outflow valve of the fluid system. This is the direct hydrodynamic consequence of the geometric setup established during portal triangulation. As long as the working portal remains patent through the muscle layer, outflow proportional to inflow is guaranteed.
When outflow is obstructed or when inflow pressure exceeds outflow capacity, working-space pressure rises and a cascade of complications begins:
(a) Pressure exceeds dural pulse pressure → CSF flow is impeded, epidural pressure spikes, and seizure may follow in severe cases. (b) Saline extravasates into the muscle layer → muscle swelling, loss of working space, prolonged postoperative pain. (c) Violation of the annulus or intertransverse membrane → potential hydroperitoneum.
The first principle of fluid management is therefore simple: always preserve outflow.
#Pressure Settings: Gravity vs Pump
The optimal hydrostatic pressure range is 30–50 mmHg. Outside this range, either visualization or safety is compromised.
Gravity system (recommended during the learning curve)
Pressure is adjusted by the height of the saline bag. The relationship is approximated by P (mmHg) ≈ h (cm) / 1.36. In practice, a bag suspended 50–70 cm above the patient's back delivers approximately 37–51 mmHg. The principal advantage of the gravity system is self-regulation — as the epidural space fills, inflow naturally diminishes, avoiding the pump-related complications described below.
Pump system
Pump systems deliver more constant pressure and therefore a cleaner visual field. They carry two specific risks: (1) pump pressure can mask active venous bleeding, exposing the bleeder only after the pump is turned off — a common pathway to postoperative epidural hematoma; (2) pump pressures above 40 mmHg increase the risk of epidural pressure spikes. When a pump is used, continuous pressure monitoring is essential, and a routine of turning the pump off and waiting 30 seconds before closure is non-negotiable.
Stage-specific recommendation
During the early learning curve — approximately the first 50 cases — the gravity system should be the default. Its self-regulating behavior provides a safety margin precisely when judgment is least developed. Pump systems are introduced once case volume has accumulated and decision-making has matured. For cases with anticipated heavy bleeding, epinephrine-containing saline irrigation has been reported to provide hemodynamic stability.
#Step 1. Initial Setup & Pressure Verification
Before entering the working space, the baseline of the fluid system must be established.
Saline bag positioning
Suspend the bag 50–70 cm above the patient's back (gravity system). Two bags connected in series provide steadier inflow. When using a pump, begin at a low inflow rate of 1.0–1.5 L/min and titrate upward while observing the field.
First inflow test
Immediately after introducing the endoscope into its portal and opening the inflow, visually confirm that saline drains freely from the working portal. This is the first evidence of outflow patency. If inflow is present but outflow is weak, the working portal has been inadequately dilated through the muscle layer — re-dilate before proceeding. Maintain inflow for 1–2 minutes in the soft-tissue plane to allow the working space to develop naturally.
Establishing the monitoring baseline
Have the assistant or scrub nurse note the baseline appearance of the paraspinal muscle around the patient's back and the tension of the skin surrounding the working portal. Ask the anesthesia team for baseline EtCO₂ and blood pressure as reference values for later comparison.
#Step 2. Maintaining Outflow During Surgery
Once setup is established, the working portal's outflow function can still be compromised by several intraoperative events. Active preservation of outflow is the essence of fluid management.
Events that threaten outflow
(a) Instrument exchange — when the instrument fully occupies the working portal, outflow is interrupted. Brief exchanges are harmless, but exchanges lasting more than 30 seconds can drive pressure upward. (b) Operating without a cannula — muscle prolapses into the portal, narrowing the outflow channel. (c) Bone work — small bone fragments cause partial outflow obstruction. (d) When the distal muscle layer forms a closed environment, working-space pressure has nowhere to dissipate.
Active management of outflow
(1) Use a cannula in the working portal — outflow is maintained through the cannula's side channels even during instrument exchange. (2) Reduce inflow during critical moments — develop the habit of lowering inflow rate during instrument exchanges and similar transient steps. (3) Perform a swelling check every 30 minutes — assess paraspinal muscle volume and skin tension around the working portal at fixed intervals. (4) Communicate with anesthesia — request immediate notification of any sudden change in airway pressure, EtCO₂, or blood pressure.
End-of-case routine
Just before closure, switch off the pump or stop the inflow and wait 30 seconds before reinspecting the working space for active bleeders. Once hemostasis is confirmed, place a drain when indicated (recommended in fusion cases).
#Common Pitfalls
(a) Pressure too high — Epidural pressure spike
Recognition: Dural pulsation weakens or disappears, the visual field suddenly clouds, and small bleeders falsely appear to have stopped. The patient may show unexplained hyperventilation, tachycardia, and hypertension; in severe cases, intraoperative seizure has been reported.
Recovery: (1) Immediately turn off the pump or lower the saline bag. (2) Stop inflow and wait until working-space pressure decreases. (3) Inform the anesthesia team and prepare for possible hyperosmolar therapy. (4) Resume at a lower pressure setting once the field has recovered.
(b) Outflow blockage — Muscle swelling
Recognition: Working-space pressure rises despite unchanged inflow. The muscle and skin around the working portal swell visibly, and saline barely escapes through the portal.
Recovery: (1) Reduce inflow immediately. (2) Replace the cannula or re-dilate the working portal. (3) Wait until saline backflow normalizes. (4) If swelling persists, extend the portal incision by 1–2 mm.
(c) Hidden bleeding masked by pump pressure
Recognition: The intraoperative field appeared clean, but the patient develops postoperative epidural hematoma. The pattern arises when pump pressure has temporarily tamponaded a venous bleeder that becomes apparent only after the pump is off.
Recovery (= prevention): (1) When using a pump, switch it off before closure without exception. (2) Wait at least 30 seconds, then reinspect the working space. (3) Control every active bleeder with RF tip or bipolar. (4) Place a drain, particularly in fusion cases.
#Pearls for the First Cases
Saline is the medium in which UBE swims. Portal triangulation defines the geometry of the working zone; fluid management defines the hydrodynamics that allow the zone to operate safely. The numbers 30–50 mmHg, 50–70 cm, and 30 seconds are only the starting point — finding the variation that fits one's own hands is the path to mastery.
#Author Note
This article provides technical instruction on fluid management principles in unilateral biportal endoscopic (UBE) surgery and does not substitute for individual clinical judgment. Pressure settings, irrigation rates, and complication thresholds should be individualized based on patient factors, surgical context, and surgeon experience.
- Park DK, Weng C, Zakko P, Choi DJ. Unilateral Biportal Endoscopy for Lumbar Spinal Stenosis and Lumbar Disc Herniation. JBJS Essential Surgical Techniques. 2023;13(2):e22.00020. doi:10.2106/JBJS.ST.22.00020.
- Castel X, d'Astorg H, Lonjon G, et al. Comparison of saline consumption between microdiscectomy, uniportal, and biportal endoscopic lumbar disc surgery: A multicenter observational study. European Spine Journal. 2025;34(12):5757–5764. doi:10.1007/s00586-025-09256-3.
- Ko WH, Cho YH, Jang W, et al. Hemodynamic protective effects of epinephrine containing saline irrigation in biportal endoscopic lumbar surgery. Medicine (Baltimore). 2022;101(30):e29311. doi:10.1097/MD.0000000000029311.
- Ju CI, Lee SM. Complications and Management of Endoscopic Spinal Surgery. Neurospine. 2023;20(1):56–77. doi:10.14245/ns.2346226.113.
- Yang L, Yu T, Jiao J, et al. Comprehensive Analysis of UBE-Related Complications: Prevention and Management Strategies from 4685 Patients. Medical Science Monitor. 2024;30:e944018. doi:10.12659/MSM.944018.
- Zhang Y, Wu J, Qin Z, et al. Clinical Features and Management of Seizure After Percutaneous Endoscopic Spine Surgery: A Retrospective Case Series Analysis. World Neurosurgery. 2022;167:e891–e903. doi:10.1016/j.wneu.2022.08.104.
- Kim JY, Ha JS, Lee CK, Lee DC, Hong HJ, Choi SY, Park CK. Comparative analysis of uniportal and biportal endoscopic transforaminal lumbar interbody fusion in early learning stage: technical considerations and radiological outcomes. Journal of Minimally Invasive Spine Surgery and Technique. 2024;9(Suppl 1):S14–23.
Hong Hyun-jin, M.D., Department of Neurosurgery, Saegijun Hospital.